December 1924, Karl Denke fails to smite Vincenz Olivier with a pickaxe. He would have been his 31st victim. The film thus reconstructs the mind, motivation, and psyche of its main character in intense dialog between him and the inspector.
When a mysterious virus created by a Japanese doctor in Tokyo escapes containment, the world spirals into chaos. A medical anomaly quickly mutates into a global phenomenon-manifesting in eerie, unpredictable forms across two continents.