Based on real events, the story follows a father and son (Offerman and Tremblay) who identify as Sovereign Citizens, a group of anti-government extremists, as they venture across the country and find themselves in a standoff with a chief of police (Dennis Quaid) that sets off an intense manhunt with tragic consequences.
When a mysterious virus created by a Japanese doctor in Tokyo escapes containment, the world spirals into chaos. A medical anomaly quickly mutates into a global phenomenon-manifesting in eerie, unpredictable forms across two continents.